World Bank Warns of Rising Threat from Chronic Hepatitis B as Vaccination Rates Slip

A new World Bank report has sounded the alarm on the global burden of chronic hepatitis B, revealing that an estimated 254 million people are living with the virus — many without even knowing it. The findings point to both encouraging progress in some areas and worrying setbacks in others, particularly in regions where vaccination coverage is declining.
The report notes that while significant gains have been made in childhood immunization, a drop in coverage in certain parts of the world threatens to undo years of progress. Health experts warn that such setbacks could open the door to a resurgence of the disease.
Data from the study shows that Sub-Saharan Africa and the East Asia & Pacific region bear the highest share of the global hepatitis B burden. This uneven distribution highlights the urgent need for region-specific strategies and greater investment in healthcare systems in affected countries. The disease’s prevalence is closely tied to income levels, with low and lower-middle-income nations facing a disproportionately high impact.
Medical experts stress that lack of awareness and delayed diagnosis are major challenges. Because hepatitis B often causes no symptoms until advanced stages, it can silently progress to serious liver damage, cirrhosis, or liver cancer if untreated.
One of the most effective defenses — childhood vaccination — is now at risk in several regions due to gaps in public health programs. Health organizations fear that slipping coverage could lead to a spike in new infections, especially among younger populations.
The World Bank is urging governments, health agencies, and community leaders to ramp up action. Recommended measures include reinforcing immunization campaigns, expanding access to affordable diagnostic tests and treatment, and boosting public awareness through education programs.
“This is a wake-up call for the global community,” the report states. “The fight against hepatitis B demands a coordinated and sustained effort if we are to achieve a future free from this disease.”
